Mabotolo a chikhalidwe cha ma cellNthawi zambiri amagwiritsidwa ntchito pazikhalidwe zama cell, pomwe ma cell amayenera kulumikizidwa pamwamba pa chinthu chothandizira kuti akule.Ndiye pali kukopa kotani pakati pa selo lotsatizana ndi chinthu chomwe chili pamwamba pa chinthucho, ndipo kachitidwe ka selo lomatira ndi chiyani?

Cell adhesion amatanthauza ndondomeko ya zomatira amadalira maselo pasting ndi kufalitsa pa chikhalidwe padziko.Kaya selo likhoza kumangirizidwa ku chikhalidwe pamwamba zimadalira makhalidwe a selo lokha, pa kuthekera kukhudzana pakati pa selo ndi chikhalidwe pamwamba, komanso ngakhale pakati pa selo ndi chikhalidwe pamwamba, zomwe zikugwirizana ndi mankhwala ndi thupi katundu wa pamwamba.

Kuchuluka kwa maselo kumakhudzananso ndi mankhwala ndi thupi la chikhalidwe chapamwamba, makamaka kachulukidwe kameneka pa chikhalidwe cha chikhalidwe.Kuzizira ndi fibronectin mu seramu kumatha kulumikiza chikhalidwe pamwamba pa cell, zomwe zimapindulitsa kufulumizitsa kuchuluka kwa ma cell.Kuphatikiza pazifukwa zomwe zili pamwambazi, kufalikira kwa maselo pamtunda wa chikhalidwe kumagwirizananso ndi mawonekedwe apamwamba, makamaka kusalala.

Maselo ambiri amtundu wa mammalian amakula mu m'galasi ndi m'galasi Ufumuyo gawo lapansi, amene m`galasi akhoza kukhala maselo ena, kolajeni, mapulasitiki, etc. Maselo woyamba secrete extracellular masanjidwewo, amene amatsatira pamwamba pa selo chikhalidwe vial.Selolo limamangiriza ku matrices owonjezerawa kudzera pa zomatira zomwe zimawonetsedwa pamwamba pake.

Kuphatikiza apo, pofuna kulimbikitsa kutsata kwa ma cell, kukula kwa botolo la chikhalidwe cha cell kudzathandizidwa mwapadera kuti adziwitse misa ya hydrophilic, yomwe imathandizira kukula kwa maselo ogwirizana.